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DeutschThe Gloria 4.2 Scmos camera features a power connector, a USB 3.1 interface, two CXP-12 interfaces, one SMA interface for trigger input, three SMA interfaces for trigger output, and two water cooling
A Scientific CMOS (sCMOS) camera is a high-performance imaging device that combines high quantum efficiency (QE), ultra-low readout noise, and high frame rates. Unlike traditional CMOS, sCMOS is engineered for low-light scientific applications where every photon counts, such as single-molecule microscopy and quantum physics research.
Revealer scientific CMOS cameras feature 95% quantum efficiency (QE), 135 fps at 2048×2048 resolution, and ultra-low 1.2e⁻ read noise. As high-sensitivity CMOS cameras, they are ideal for applications such as cell biology, quantum physics, cold atom research, spectroscopy, microscopy, and astrophotography. Designed with deep cooling and high-speed data transfer, Revealer scientific CMOS cameras deliver superior low-light imaging performance for advanced scientific research.
Equipping multiple labs or facilities with high-performance sCMOS cameras? Our bulk order program delivers exceptional value while maintaining the scientific-grade quality Revealer is known for.
Why Order in Volume from Revealer?
Significant Cost Savings: Structured discounts that increase with order quantity
Consistent Performance: Every camera undergoes identical rigorous testing and calibration
Simplified Procurement: Single vendor, unified support, streamlined documentation
Future-Proof Investment: Compatible software updates and long-term spare parts availability
Request a custom quote for your institution's specific sCMOS camera needs.
Not all scientific research requires the same imaging priorities. Use the table below to compare the key specifications of the Revealer Gloria sCMOS series and find the ideal match for your lab’s requirements.
| Model | Resolution | Pixel Size | Max Frame Rate | Primary Strength | Best Application |
| Gloria 6504 | 6.5 MP | 6.5 μm | 100 FPS | High Resolution & HDR | General Research, Material Science, HDR Imaging |
| Gloria 1605 | 1.6 MP | 16 μm | 100 FPS | Ultimate Sensitivity | Single Photon Detection, Faint Signal, Spectroscopy |
| Gloria 1104 | 1.1 MP | 11 μm | 120 FPS | Wide Field of View | Astronomy, EMCCD Replacement, Cold Atom Research |
| Gloria 4.2 | 4.2 MP | 6.5 μm | 135 FPS | Balanced Performance | Fluorescence Microscopy, Life Sciences, Quantum Physics |
Gloria 6504 is a new-generation back-illuminated sCMOS camera featuring high sensitivity, high frame rate, and high dynamic range. Equipped with Gpixel's scientific-grade image sensor, combined wi...
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Revealer sCMOS camera Gloria1605 boasts outstanding quantum efficiency, 16μm large pixels, and sub-electron readout noise. It breaks through traditional limitations to tackle challenging photon detection in scientific research, offering precise and efficient imaging to capture faint single-photon signals that would otherwise be lost, enabling deeper scientific insights.
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Revealer sCMOS camera Gloria1104 offers 95% peak quantum efficiency, 11μm large pixels, and low-light detection similar to EMCCD. Its 32mm large diagonal field of view broadens its application range, making it ideal for ultra-low-light fields like biology, physics, astronomy, and spectral detection.
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Revealer sCMOS camera Gloria4.2 is a back-illuminated (BSI) sCMOS camera offering high sensitivity, fast frame rates, and wide dynamic range. With a Gpixe scientific-grade sensor, deep-cooled hermetic packaging, and high-speed data transfer, it excels in low-light imaging with high SNR. It is commonly used in life sciences, quantum physics, and other applications, easily integrating into optical detection systems.
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For decades, Electron-Multiplying CCD (EMCCD) was considered the gold standard for ultra-low-light imaging. However, with the advent of back-illuminated scientific CMOS technology, Revealer sCMOS cameras have redefined the performance benchmarks for modern scientific research.
Here is why many leading laboratories are transitioning from EMCCD to sCMOS:
1. Higher Speed without Compromise
EMCCDs are inherently limited by their serial readout architecture, often struggling to exceed 30 fps at full resolution. In contrast, Revealer sCMOS cameras achieve 100+ fps at 4.2MP or higher resolution, enabling the capture of fast biological processes and transient quantum phenomena that EMCCDs simply miss.
2. Superior Signal-to-Noise Ratio (SNR)
While EMCCDs use gain to overcome read noise, they introduce an "Excess Noise Factor" that effectively halves the quantum efficiency. sCMOS technology eliminates this factor entirely. With ultra-low read noise (<1.2e⁻) and high raw QE (95%), sCMOS provides a cleaner, more accurate signal for medium-to-low light levels.
3. Massive Field of View (FOV)
EMCCD sensors are typically small (often 13mm diagonal), which limits the throughput of data collection. Our Gloria sCMOS series offers sensors up to 32mm diagonal, allowing researchers to monitor much larger areas—such as a whole slide or an entire astronomical sector—in a single frame.
4. Dynamic Range and Linearity
sCMOS provides a significantly higher dynamic range (up to 16-bit), allowing you to capture both very bright and very faint signals in the same image. Unlike EMCCD, sCMOS does not suffer from "pixel blooming," ensuring precise quantitative data across the entire sensor.
| Feature | EMCCD Technology | Revealer sCMOS (Gloria Series) |
| Quantum Efficiency | ~90% | Up to 95% (Back-Illuminated) |
| Excess Noise Factor | 1.41 (Adds noise) | 1.0 (No excess noise) |
| Max Frame Rate | Low (~30 fps) | High (100 - 135+ fps) |
| Field of View | Limited (Small Sensors) | Large (Up to 32mm Diagonal) |
| Readout Noise | <1e- (with gain) | 1.2e- (Raw, ultra-stable) |
The Gloria 4.2 Scmos camera features a power connector, a USB 3.1 interface, two CXP-12 interfaces, one SMA interface for trigger input, three SMA interfaces for trigger output, and two water cooling
The lens interface is C-mount, and it supports conversion to F-mount via an adapter ring.
The Gloria 4.2 camera is equipped with a USB 3.1 interface and two CXP-12 interfaces. The USB 3.1 interface is characterized by its ease of use; simply connect the USB cable to the USB 3 port on the computer. The CXP interface, on the other hand, is characterized by its high data transfer rate. When using it, a computer (usually a desktop) needs to be equipped with a CXP frame grabber card, and the camera must be connected to the interface of the CXP frame grabber card using a CXP cable.
The Gloria 4.2 camera offers two methods for secondary development:
One method is to utilize the software SDK provided by the camera software and the demo code.
The other method is to perform secondary development using the GenICam protocol. The Gloria 4.2 camera provides a GenICam-supported .cti file for both USB and CXP modes. Users can also use these two .cti files to conduct secondary development in a manner that complies with the GenICam standard protocol.
The software currently officially supports two models of frame grabber cards, which are shipped randomly. They are the Hikvision MV-GY1004IOL and the ActiveSilicon AS-FBD-4XCXP12-3PE8.
Yes, as a manufacturer, we provide extensive customization options including: alternative sensor configurations, specialized cooling requirements, custom mechanical interfaces, modified firmware for specific triggering schemes, and tailored software SDKs. Minimum order quantities for custom configurations start at 5 units, with engineering support throughout the development process.
All Revealer sCMOS cameras are certified for CE (European Union), FCC (United States), and RoHS compliance. Our manufacturing facility is ISO 9001:2015 certified, ensuring consistent quality control. Additional certifications can be obtained based on specific market requirements with sufficient order volumes.
While EMCCDs excel at single-photon counting, modern sCMOS cameras offer several advantages: higher resolution (up to 4K), faster frame rates (135+ fps), larger field of view, no excess noise factor, and better dynamic range. For most live-cell imaging, super-resolution, and high-throughput applications, sCMOS provides better overall performance.
Yes. Our cameras come with drivers and SDKs compatible with all major imaging software including µManager, Micro-Manager, NIS Elements, ZEN, SlideBook, and custom LabVIEW/MATLAB integrations. We provide comprehensive API documentation for secondary development.
95% QE means the camera converts 95% of incoming photons into electrons. This is critical for ultra-low light applications like fluorescence microscopy and cold atom research, where signal intensity is extremely weak.
Yes, we provide a comprehensive SDK and drivers for major platforms including LabVIEW, MATLAB, and C++/Python, ensuring seamless integration into your experimental workflow.
A scientific camera is designed for quantitative low-light detection. It emphasizes low noise, linearity, and absolute photon-to-electron conversion. Industrial cameras often prioritize speed and on-board image processing, which may sacrifice the quantitative accuracy required for research.
Cooling dramatically reduces the dark current (thermal noise). Lower dark current means you can use longer exposures and detect fainter signals. Our Gloria 4.2 camera reaches -15 °C with air cooling and -25 °C with water cooling at 25 °C ambient.
High-Speed: maximum frame rate, suited for dynamic samples.
CMS (Correlated Multiple Sampling): lowest read noise, ideal for extremely low light (e.g., single-molecule fluorescence).
HDR (High Dynamic Range): simultaneously reads a high-gain and low-gain signal, preserving details in both bright and dark regions in a single shot.
Binning combines neighboring pixels into one larger super-pixel before readout, improving signal-to-noise but reducing resolution. ROI only reads out a selected rectangular region of the sensor, increasing frame rate without changing pixel size.
Increase the exposure time
Use Binning (e.g., 2×2)
Apply high analog gain in weak-light conditions
Cool the sensor to the lowest temperature
Average several frames
If applicable, switch to a back-illuminated sensor with higher quantum efficiency
This is likely amplifier glow, a weak near-infrared emission from the sensor's readout circuitry. It can be removed by subtracting a dark-frame image taken under identical conditions (exposure time, temperature) using the software's correction function.
Air cooling: convenient, no external equipment needed.
Water cooling: achieves about 10 °C deeper cooling, eliminates the tiny vibrations from the fan, and is recommended for high-magnification microscopy where stability is critical. It requires an external water chiller.
It features USB 3.1 for easy connection, 2 × CoaXPress-12 (CXP-12) for maximum data throughput, 1 × trigger input and 3 × trigger output (SMA connectors), plus two water-cooling tubes. The lens mount is C-mount (F-mount via adapter).
Windows Photo Viewer can only display 8-bit images. To see a 16-bit image correctly, open it with a scientific image viewer such as ImageJ, or export an 8-bit version for preview.
Life science: fluorescence microscopy, super-resolution, live-cell imaging
Astronomy: adaptive optics, space-debris tracking, solar observation
Physical science: quantum optics, atomic physics, spectroscopy
Any application that requires quantitative, low-noise detection of weak optical signals.
